2012•Journal of Medical Science Yanbian UniversityRequires access

Correlation analysis between the impaired fasting glucose and multiple metabolic indexes

Fang Jin-n

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Abstract

OBJECTIVE To analyze the correlation between impaired fasting glucose(IFG) and multiple metabolic indexes in Korean-Chinese and Han nationality of Yanbian area.METHODS 3 217 cases of inhabitants aged 30-70 years in Korean-Chinese and Han nationality of Yanbian areas were selected by a simple random sampling method,and all subjects knew the informed consent.The data about the general information were collected by the family visit,and height,weight,waist circumference(WC) and blood pressure was measured by physical examination,and total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),fasting blood glucose(FBG),blood uric acid(UA),gamma glutamyl transferase(GGT) and fasting insulin(FINS) were measured from fasting venous blood.RESULTS As compared with the normal group,the IFG group had higher mean level of BMI,WC,HDL-C,TG,UA and HOMA-IR,and had lower mean level of HOMA-β and ISI after adjustment for sex,race,age,smoking,drinking and education(P0.001).Partial correlation analysis showed that there was a positive correlation between FBG and BMI,WC,SBP,DBP,TC,HDL-C,TG,HOMA-IR,UA as well as GGT(P0.05,P0.01),and a negative correlation with HOMA-β and ISI(P0.01).CONCLUSION The IFG and FBG are closely correlated with multiple metabolic indexes.

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OBJECTIVE To analyze the correlation between impaired fasting glucose(IFG) and multiple metabolic indexes in Korean-Chinese and Han nationality of Yanbian area.METHODS 3 217 cases of inhabitants aged 30-70 years in Korean-Chinese and Han nationality of Yanbian areas were selected by a simple random sampling method,and all subjects knew the informed consent.The data about the general information were collected by the family visit,and height,weight,waist circumference(WC) and blood pressure was measured by physical examination,and total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),fasting blood glucose(FBG),blood uric acid(UA),gamma glutamyl transferase(GGT) and fasting insulin(FINS) were measured from fasting venous blood.RESULTS As compared with the normal group,the IFG group had higher mean level of BMI,WC,HDL-C,TG,UA and HOMA-IR,and had lower mean level of HOMA-β and ISI after adjustment for sex,race,age,smoking,drinking and education(P0.001).Partial correlation analysis showed that there was a positive correlation between FBG and BMI,WC,SBP,DBP,TC,HDL-C,TG,HOMA-IR,UA as well as GGT(P0.05,P0.01),and a negative correlation with HOMA-β and ISI(P0.01).CONCLUSION The IFG and FBG are closely correlated with multiple metabolic indexes.

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Available abstract

OBJECTIVE To analyze the correlation between impaired fasting glucose(IFG) and multiple metabolic indexes in Korean-Chinese and Han nationality of Yanbian area.METHODS 3 217 cases of inhabitants aged 30-70 years in Korean-Chinese and Han nationality of Yanbian areas were selected by a simple random sampling method,and all subjects knew the informed consent.The data about the general information were collected by the family visit,and height,weight,waist circumference(WC) and blood pressure was measured by physical examination,and total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),fasting blood glucose(FBG),blood uric acid(UA),gamma glutamyl transferase(GGT) and fasting insulin(FINS) were measured from fasting venous blood.RESULTS As compared with the normal group,the IFG group had higher mean level of BMI,WC,HDL-C,TG,UA and HOMA-IR,and had lower mean level of HOMA-β and ISI after adjustment for sex,race,age,smoking,drinking and education(P0.001).Partial correlation analysis showed that there was a positive correlation between FBG and BMI,WC,SBP,DBP,TC,HDL-C,TG,HOMA-IR,UA as well as GGT(P0.05,P0.01),and a negative correlation with HOMA-β and ISI(P0.01).CONCLUSION The IFG and FBG are closely correlated with multiple metabolic indexes.

Key concepts: Internal medicine, Impaired fasting glucose, Medicine, Waist, Triglyceride, Endocrinology, Blood pressure, Uric acid

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