Propess for Promotion of Cervical Ripening in Full-term Pregnancy

Objective: To explore the efficacy and safety of Propess for induction of cervical ripening and vaginal delivery in term pregnancies.Methods: 120 cases of term pregnancies were randomly divided into experimental group and control group.Propess was in-serted in posterior vaginal fornix in 60 cases for 1~2 times,and the control group was treated with microoxytocin.The cervical maturity,time from administration to delivery,stages of labor,rate of vaginal delivery,and side effects of drugs were compared between the two groups.Results: ①The increase of Bishop's score was 3.81±1.04 in experimental group,significantly higher than 3.09±1.15 in control group(P0.05).② The treatment of Propess was more effective in the experimental group than the control group(excellence rate 78.33% vs 35.00%,total effective rate.91.67% vs 63.33%)(P0.01).③ In experimental group,the rate of vaginal delivery was 73.33%,time from administration to delivery 34.19±13.20h,time for labor stages 8.47±2.68h,while in the control group 41.67%,52.14±16.05h and 12.25±3.73h respectively.Difference between the two groups was statistically significant(P0.01 or 0.05).④ The difference of postpar-tum hemorrhage(225.31±67.80ml vs 232.44±75.76ml),birth weight(3369.48±311.65g vs 3417.63±359.68g),and Apgar's scores(9.52±0.39 vs 9.48±0.47) was not significant between the experimental group and control group(P0.05).Conclusion: Propess could promote the cervical ripening of term pregnancies,increase the successful rate of vaginal delivery and decrease the cesarean section rate effectively and safely.