Effects of Liquor on Oxidative Damage of Drosophila and Mice

The effects of famous liquor on drosophila's SOD,GSH-Px and mice's GSH-Px,CP,AST and ALT were studied.And the results were as follows: in the liver,compared with model group and contrast group,the activity of GSH-Px was higher in 5 % and 15 % group and the difference was statistically significant(P0.05).In each dose group the content of CP were higher than that in blank group and the difference was also statistically significant(P0.05).Compared with the blank group,the content of AST in 5 % group was not statistically significant.But the dose groups(15 %,30 % and 60 %) and alcohol group(30 %) were significantly higher than blank group.In blood serum,compared with other control groups,the content of ALT was higher in alcohol group(30 %).In the experiment of drosophila,the activity of SOD and GSH-Px were lower in alcohol group(0.3 mL/kg) compared to blank and low doses famous liquor groups,and the difference was statistically significant(P0.05).All the results showed that the toxicity of famous liquor was smaller than alcohol and famous liquor under low dose could depress the oxidative damage in mice and drosophila.