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2007•Zhongguo yixue wulixue zazhiRequires access

Effect of Electric Fields on Experimental Spinal Cord Injury in Rats

Yong Wang

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Abstract

Objectives: To investigate the effect of electric fields(EF) on spinal cord blood flow(SCBF) and the function after spinal cord injury(spinal cord injury,SCI).Methods: A total of 20 Wistar rats were randomly divided into control group(CON)and EF treated group(EF).EF was given into rats immediately after traumatic injury of the L1~L2 segmental spinal cord was made by using Allen's method 50 gcm(5 g×10 cm).The SCBF and sensory evoked potential(SEP) of T12 segment were recorded before injury and at 0,1,3,6,and 24 h after injury.Combined behavioral scores(CBS) were assessed 7 and 14 days after surgery.Results: SCBF and SEP of rats treated with EF were much higher than those of the rats in group CON(P 0.05).Conclusions: EF can improve the spinal cord blood flow and protect the functions of injured spinal cord.

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What this paper is about

Objectives: To investigate the effect of electric fields(EF) on spinal cord blood flow(SCBF) and the function after spinal cord injury(spinal cord injury,SCI).Methods: A total of 20 Wistar rats were randomly divided into control group(CON)and EF treated group(EF).EF was given into rats immediately after traumatic injury of the L1~L2 segmental spinal cord was made by using Allen's method 50 gcm(5 g×10 cm).The SCBF and sensory evoked potential(SEP) of T12 segment were recorded before injury and at 0,1,3,6,and 24 h after injury.Combined behavioral scores(CBS) were assessed 7 and 14 days after surgery.Results: SCBF and SEP of rats treated with EF were much higher than those of the rats in group CON(P 0.05).Conclusions: EF can improve the spinal cord blood flow and protect the functions of injured spinal cord.

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Available abstract

Objectives: To investigate the effect of electric fields(EF) on spinal cord blood flow(SCBF) and the function after spinal cord injury(spinal cord injury,SCI).Methods: A total of 20 Wistar rats were randomly divided into control group(CON)and EF treated group(EF).EF was given into rats immediately after traumatic injury of the L1~L2 segmental spinal cord was made by using Allen's method 50 gcm(5 g×10 cm).The SCBF and sensory evoked potential(SEP) of T12 segment were recorded before injury and at 0,1,3,6,and 24 h after injury.Combined behavioral scores(CBS) were assessed 7 and 14 days after surgery.Results: SCBF and SEP of rats treated with EF were much higher than those of the rats in group CON(P 0.05).Conclusions: EF can improve the spinal cord blood flow and protect the functions of injured spinal cord.

Key concepts: Spinal cord, Spinal cord injury, Medicine, Anesthesia, Cord, Blood flow, Surgery, Internal medicine

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