Investigation of Hepatitis B Virus Infection And Immune Status In Penglai's Rural Areas

Objective To investigate the status of hepatitis B virus(HBV) infection and carrying rate of hepatitis B antigen in rural areas;to evaluate both the management of childrens' immune about hepatitis B vaccine in 1992 and childrens' immune programming effect in 2002.Menthods Using a multi-stage random sampling methods,to investigate hepatitis B epidemiology and Hepatitis B vaccine rate in 629 rural residents aged from 1 to 59 years old, enzyme-linked immunosorbent assay(ELISA) was taken to detect HBsAg,anti-HBs,anti-HBc etc.Results In total 629 respondents,HBV infection rate was 22.26%,positive rate of HBsAg,anti-HBs,anti-HBc respectively was 2.70%,62.32%,and 18.44%.In 1～59 years old crowd,the positive rate of HBsAg during people who Vaccinated with hepatitis B vaccine was 0.84%,was obviously lower than those without the hepatitis B vaccine immune,the difference was statistically significant(P0.005);the anti-HBs positive rate was 81.74%,obviously was higher than those who without,the difference was statistically significant(P0.005);positive rate of female with the anti- Hbc was significantly higher than the male(P0.05).People who was bom before 1992,their HBsAg positive rate was 4.34%,which was obviously higher than the people who was bom between hepatitis B vaccine immune management period (1991-2001) and after the period(after 2002),the difference was statistically significant(P0.05).People who was bom before 1992,their anti-HBs positive rate was 42.11%,which was obviously lower than the people who was bom between hepatitis B vaccine immune management period(1991-2001) and after the period(after 2002),the difference was statistically significant(P0.005).Conclusion With the help of hepatitis B vaccine since 1992,both the Hepatitis B virus carrying status and the effect of protection rate of Hepatitis B surface antibody were improved.Suggestion From now on,we shoud strive to spread the experiences of people with hepatitis B vaccine immune plan to the people without,and strengthen the adult hepatitis B vaccine inoculation efforts.