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Changes of the cerebral white matter anisotropy in the depressives

Miao Guang-shen

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Abstract

Objective:To investigate changes of the cerebral white matter anisotropy in the depressives by using diffusion tensor MR imaging.Methods:9 depressives were studied using MR diffusion tensor imaging compared with 10 healthy adults.The fractional anisotropy(FA) values were measured.The ROIs were put in the frontal,temporal,occipital lobe and callosum respectively.Results:Comparing with healthy adult,significant difference of the FA values of white matter was found in bilateral frontal lobe,temporal lobe and splenium of corpus callosum in the depressives.Conclusion:There is a tenuous FA value reduction in the depresives compared with healthy adult,and the FA values in the left frontal lobe and temporal lobe are different from the right ones.

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What this paper is about

Objective:To investigate changes of the cerebral white matter anisotropy in the depressives by using diffusion tensor MR imaging.Methods:9 depressives were studied using MR diffusion tensor imaging compared with 10 healthy adults.The fractional anisotropy(FA) values were measured.The ROIs were put in the frontal,temporal,occipital lobe and callosum respectively.Results:Comparing with healthy adult,significant difference of the FA values of white matter was found in bilateral frontal lobe,temporal lobe and splenium of corpus callosum in the depressives.Conclusion:There is a tenuous FA value reduction in the depresives compared with healthy adult,and the FA values in the left frontal lobe and temporal lobe are different from the right ones.

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Available abstract

Objective:To investigate changes of the cerebral white matter anisotropy in the depressives by using diffusion tensor MR imaging.Methods:9 depressives were studied using MR diffusion tensor imaging compared with 10 healthy adults.The fractional anisotropy(FA) values were measured.The ROIs were put in the frontal,temporal,occipital lobe and callosum respectively.Results:Comparing with healthy adult,significant difference of the FA values of white matter was found in bilateral frontal lobe,temporal lobe and splenium of corpus callosum in the depressives.Conclusion:There is a tenuous FA value reduction in the depresives compared with healthy adult,and the FA values in the left frontal lobe and temporal lobe are different from the right ones.

Key concepts: Splenium, Fractional anisotropy, Corpus callosum, White matter, Diffusion MRI, Medicine, Frontal lobe, Temporal lobe

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