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Quantitative analysis anisotropy of normal adult cerebral white matter fiber by using diffusion-tensor MR imaging

HE Guang-wu

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Abstract

Objective To quantitatively analyze the difference of anisotropy of the different cerebral white matter fiber. Methods A total of 52 healthy adult volunteers were studied using MR diffusion tensor imaging. The FA values and ADC values were measured. The ROIs were placed in external capsule, anterior limb of the internal capsule, posterior limb of the internal capsule, genu of corpus callosum, splenium of corpus callosum. Results The FA value of the splenium of the corpus callosum was the highest(0.893±0.0645). There was statistical difference of FA value between the ROIs of this study( P 0.01).Conclusion FA value can be used to quantitatively analyze the anisotropy of different cerebral white matter fiber.

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What this paper is about

Objective To quantitatively analyze the difference of anisotropy of the different cerebral white matter fiber. Methods A total of 52 healthy adult volunteers were studied using MR diffusion tensor imaging. The FA values and ADC values were measured. The ROIs were placed in external capsule, anterior limb of the internal capsule, posterior limb of the internal capsule, genu of corpus callosum, splenium of corpus callosum. Results The FA value of the splenium of the corpus callosum was the highest(0.893±0.0645). There was statistical difference of FA value between the ROIs of this study( P 0.01).Conclusion FA value can be used to quantitatively analyze the anisotropy of different cerebral white matter fiber.

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Available abstract

Objective To quantitatively analyze the difference of anisotropy of the different cerebral white matter fiber. Methods A total of 52 healthy adult volunteers were studied using MR diffusion tensor imaging. The FA values and ADC values were measured. The ROIs were placed in external capsule, anterior limb of the internal capsule, posterior limb of the internal capsule, genu of corpus callosum, splenium of corpus callosum. Results The FA value of the splenium of the corpus callosum was the highest(0.893±0.0645). There was statistical difference of FA value between the ROIs of this study( P 0.01).Conclusion FA value can be used to quantitatively analyze the anisotropy of different cerebral white matter fiber.

Key concepts: Splenium, Corpus callosum, Internal capsule, Medicine, Diffusion MRI, White matter, Fractional anisotropy, External capsule

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