Therapeutic effect of magnesium isoglyeyrrhizinate on chronic hepatitis B

Objective To observe the therapeutic effects and drug safety of magnesium isoglyeyrrhizinate on chronic hepatitis B.Methods 178 patients of chronic hepatitis B were randomly divided into 3 groups,including high dose of magnesium isoglycyrrhizinate group(200mg of intravenous drop infusion administration),low dose of magnesium isoglycyrrhizinate group(100mg of intravenous drop infusion administration) and diammonium glycyrrhizinate group(150mg of intravenous drop infusion administration).Results The improvement rates of symptom,clinical signs and liver function of magnesium isoglycyrrhizinate administrations was more obvious than that of diammonium glycyrrhizinate group.There was no serious adverse effect after treatment.Conclusion The therapeutic effect of magnesium isoglycyrrhizinate was better than that of diammonium glycyrrhizinate for chronic hepatitis B.