The Treating Effect on the Left Ventricular Hypertrophy in Patients with Congestive Heart Failure

Objective To evaluate the effects of angiotensin-converting enzyme inhibition ( ACEI) and beta receptor blockers ( β-B) on the old patients with congestive heart failure. Methods Choose 102 cases as CHF group elderly. At the same time,102 cases with CHF in elderly were divided randomly into four groups: A group ( the routine therapy group,n = 23) treated with digitals,diuretics,nitrates; B group ( enalapril group,n = 23) treated with enalapril and the above toutine therapy; C group ( metoprolo group,n = 23) reated with enalapril and the above toutine therapy; D group ( enalapril combined with metoprolo group,n = 23) reated with enalapril and metoprolo on the basis of toutine therapy; All of groups were treated for three months. With Doppler ultra-sonic apparatus,the size of left ventricular diastasis diameter ( LVEDD) ,left ventricular diastasis volume ( LVEDV) and left ventricular ejection fraction ( LVEF) in 102 patients were measured,and the results were analysed. Results After three month treatment,in enalapril group and metoprolo group,LVEDD and LVEDV were lower in normol con-trol group,while LVEF was higher than that. After three months treatment,the changes of LVEDD,LVEDV and LVEF between enalapril group and metoprolo group did not reach statistical significant ( P 0. 05) . After three months treatment,in enalapril combined with metoprolo group,had lower LVEDD and LVEDV than enalapril group and metoprolo group,while LVEF was higher ( P 0. 01) . Conclusion Both enalapril and metoprolo not only can put off left ventrieular hypertrophy and remodeling but also can improve prognosis.