Analysis of measles,rubella and mumps antibody level in healthy people in Jiangsu province in 2012
Yin Hu
Abstract
Yin Hu
Abstract
Objective To understand and master the immunization status of measles,rubella and mumps in healthy population at different age in Jiangsu province,to monitor the antibody level,so as to provide basis for prevention and control of measles,rubella and mumps. Methods Normal people in 3 cities of Jiangsu province were divided into 10 age groups( 0 ~ 7 months old,8 ~ 17 months old,1. 5 ~ 2 years old,3 ~ 4 years old,5 ~ 6 years old,7 ~ 9 years old,10 ~ 14 years old,15 ~ 19 years old,more than 20 years old,floating population more than 20 years old),and the IgG antibody of measles,rubella,mumps were detected using ELISA,then the positive rates and geometric mean concentration( GMC) of antibody were calculated. Results The specimens of 1502 cases were detected for measles,rubella and mumps. There was no statistical significance difference in positive rate and GMC of measles,rubella,mumps antibody among different age groups. Conclusion The positive rates of measles and rubella antibody in healthy population were higher in Jiangsu province,less risk for outbreak or epidemic in large range,but low positive rate was still found in several age groups,need to strengthen the immune. The positive rate of mumps antibodies was slightly low,so individual age group need to strengthen the immunity or change existing immunization strategy.
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Objective To understand and master the immunization status of measles,rubella and mumps in healthy population at different age in Jiangsu province,to monitor the antibody level,so as to provide basis for prevention and control of measles,rubella and mumps. Methods Normal people in 3 cities of Jiangsu province were divided into 10 age groups( 0 ~ 7 months old,8 ~ 17 months old,1. 5 ~ 2 years old,3 ~ 4 years old,5 ~ 6 years old,7 ~ 9 years old,10 ~ 14 years old,15 ~ 19 years old,more than 20 years old,floating population more than 20 years old),and the IgG antibody of measles,rubella,mumps were detected using ELISA,then the positive rates and geometric mean concentration( GMC) of antibody were calculated. Results The specimens of 1502 cases were detected for measles,rubella and mumps. There was no statistical significance difference in positive rate and GMC of measles,rubella,mumps antibody among different age groups. Conclusion The positive rates of measles and rubella antibody in healthy population were higher in Jiangsu province,less risk for outbreak or epidemic in large range,but low positive rate was still found in several age groups,need to strengthen the immune. The positive rate of mumps antibodies was slightly low,so individual age group need to strengthen the immunity or change existing immunization strategy.
Key concepts: Measles, Rubella, Medicine, Immunization, Population, Outbreak, Pediatrics, Immunology