2005•Journal of Zhengzhou UniversityRequires access

Biologic characteristics of human bone marrow-derived mesenchymal stem cells cultured in vitro

Fa Xian

Abstract

Aim: To investigate the biological characteristics of human bone marrow-derived mesenchymal stem cells (MSCs) in vitro. Methods: Human MSCs were isolated from bone marrow and purified by centrifuge and cultured in vitro. The proliferation and growth characteristics of MSCs were observed in primary and passage culture. Results: Human bone marrow-derived MSCs showed active proliferation capacity in vitro in primary and passage cultures.Conclusion: MSCs derived from human bone marrow have been successfully cultured. It founds a base for further investigation and using of mesenchyaml stem cells.

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Key concepts: Mesenchymal stem cell, Human bone, In vitro, Bone marrow, Stem cell transplantation for articular cartilage repair, Stem cell, Cell biology, Chemistry