Explore predictors of recurrent or residual for severe cervical intraepithelial neoplasia after loop electrosurgical excision procedure

Objective To explore predictors of recurrent or residual for severe cervical intraepithelial neoplasia(CIN)after loop electrosurgical excision procedure(LEEP).Methods Eighty-six outpatients with high-risk human papillomavirus(HR-HPV)infecting CIN Ⅱ~CIN Ⅲ confirmed by histology were treated by LEEP.Follow-up by two years,HR-HPV load was measured.Meanwhile,cervical cytology,colposcopy and cervical biopsy were performed.Results HR-HPV was a sensitive predictor for disease remaining or relapsing after LEEP,but its specificity was not as good as cervical cytology's(P0.05).Conclusion During the follow-up after LEEP,we should measure HR-HPV load to identify the high-risk groups for residual or recurrent of the lesions.Meanwhile,cervical cytology should be combined with in order to enhance the specificity of the forecast.