2009•Chinese Journal of Hospital PharmacyRequires access
Effects of Qianlie Yutong liquid on prostatitis rat and its anti-inflammatory and analgesia activity
Yu Jia
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Abstract
OBJECTIVE To investigate the effects of Qianlie Yutong liquid on chronic nonbacterial prostatitis and its anti-inflammatory and analgesia activity.METHODS Chronic nonbacterial prostatitis model was induced by injecting carrageengel solution into the prostate of rat,and then the changes of WBC number,lecithin corpuscular density and prostatic histomorphology were observed.Anti-inflammatory effects were studied by dimethylbenzene-induced ear tumefaction,analgesia activity was tested by hot-plate model and auricle circulation was observed in mice.RESULTS Qianlie Yutong liquid markedly reduced WBC,increased lecithin corpuscular density,decreased inflammatory cell infiltration of prostatic tissue in rats,lessened ear tumefaction,elevated the latency in hot-plate model and improved auricle tiny circulation in mice.CONCLUSION Qianlie Yutong liquid has the effect on experimental chronic nonbacterial prostatitis.