Laboratory tests and clinical significance of D-2 dimer in patients with disseminated intravascular coagulation

Objective To evaluate the amount of D-2 dimer in patients with disseminated intravascular coagulation(DIC),and explore the clinical value of D-2dimer examination in patients with DIC.Methods D-2 dimer examination was taken on 30cases of DIC patients(DIC group)and 30cases of non DIC patients(control group)in our hospital,and DIC levels of the two groups were compared.30 cases of DIC were divided into three groups:high coagulation stage group,consumption of low freezing group and fibrinolytic stage,according to DIC staging at the same time,the amount of D-2dimer in patients with disseminated intravascular coagulation(DIC)in different period was compared and the relationship between them were explored.Results The amount of D-2dimer in patients with DIC were higher than the control group(t=11.229,P=0.000),which was the highest in fibrinolytic stage patients and the second in low freezing consumption period and the lowest hypercoagulable period(Z=-4.785,P=0.000).At the same time,DIC dimer levels and DIC stage in patients with D-2 had positive linear correlation(R=0.982,P=0.000).Conclusion The amount of D-2 dimer in DIC patients was significantly higher than non DIC patients,and the amount of D-2 dimer has differences in different DIC stages,which can be used in the prediction of DIC patients.