SYNTHESIS AND SURFACTANT PROPERTIES OF ROSINOYL GLUTAMIC ACID
Xie Wen
Abstract
Xie Wen
Abstract
Rosinoyl chloride was prepared from rosin acid and PCl 3 at yield over 84%. Rosinoyl glutamic acid was synthesized by condensation of rosinoyl chloride with glutamic acid in 50%aqueous acetone. Orthogonal experiment result shows that the optimum synthetic conditions were as follows: molar ratio of rosinoyl chloride to glutamic acid 1∶0.8,reaction time 2.5 h,reaction temperature 25~30 ℃,pH 7~8, yield 84%. Surfactant properties of sodium rosinoyl glutamate were also determined.
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Rosinoyl chloride was prepared from rosin acid and PCl 3 at yield over 84%. Rosinoyl glutamic acid was synthesized by condensation of rosinoyl chloride with glutamic acid in 50%aqueous acetone. Orthogonal experiment result shows that the optimum synthetic conditions were as follows: molar ratio of rosinoyl chloride to glutamic acid 1∶0.8,reaction time 2.5 h,reaction temperature 25~30 ℃,pH 7~8, yield 84%. Surfactant properties of sodium rosinoyl glutamate were also determined.
Key concepts: Chemistry, Glutamic acid, Pulmonary surfactant, Yield (engineering), Resin acid, Acetone, Chloride, Aqueous solution