Clinical Significance of Brain Natriuretic Peptide combined with Hypersensitive C reactive protein and D-dimer in Acute Myocardial Infarction

Objective We conducted a trial to explore the clinical significance of brain natriuretic peptide combined with hypersensitive C reactive protein and D-dimer in acute myocardial infarction.Methods We assessed profiles of brain natriuretic peptide,hypersensitive C reactive protein and D-dimer in 37 primary AMI patients complicated by the Gensini score compared with 20 healthy persons as contorl.The blood samples were obtained within 24 hours after the onset of AMI were separated by centrifugation immediately and they were tested within 12 hours under 4℃.Results 1.The BNP,hs-CRP,D-D and CTn-I levels in AMI are all higher than in Ctrl group.2.The BNP,hs-CRP andD-D levels in KⅡ-Ⅳare all higher than in KⅠgroup.3.BNP and hs-CRP level are both related to Gensini Score.4.BNP level is related to hs-CRP level.Conclusion brain natriuretic peptide,hypersensitive C reactive protein and D-dimer have high sensitivity in AMI patients and they are helpful to assess the state of AMI patients.