Clinical and MRI analysis of pituitary stalk interruption syndrome

Objective To analyze the clinical and MRI features of pituitary stalk interruption syndrome to improve the diagnostic level of this disease. Methods The clinical and imaging data of 14 patients with pituitary stalk interruption syndrome were retrospectively analyzed, combining with reviewing of literature. Results In all 14 cases, the blood hormone tests showed growth hormone deficiency and mulitiple adenohypophyseal hormone deficiency. With MRI examination, the pituitary stalk were not shown in 12 cases, obviously thin pituitary stalk in 2 cases, and ectopic posterior lobe and decreased anterior lobe in 14 cases. Conclusion MRI is the most valuable imaging modality for the diagnosis of pituitary stalk interrup tion syndrome.