ScholarLens Back to search
2007•Di-san junyi daxue xuebaoRequires access

Clinical significance of five serum markers in diagnosis of breast cancer

Yan Zhou

Open publisher page 0 citations

Abstract

Objective To investigate the clinical value of detecting five serum markers:CA15-3,CA125,CEA,CYFRA21-1 and TPS in different combination for diagnosis of breast cancer.Methods The five serum markers were detected by enzyme linked immunosorbent assay in 48 cases of breast cancer and 20 cases of benign breast diseases.Results The levels and the positive rates of the five serum markers in breast cancer patients were significantly higher than those of benign breast disease patients.The sensitivity of breast cancer by detecting the five serum markers respectively was 54.2%,47.9%,29.1%,43.75% and 31.25%,and that was 87.5% by CA15-3 plus CA125.Conclusion The serum markers--CA125,CA15-3 and CYFRA21-1 were much more sensitive markers,and the combined detection of CA125 and CA15-3 was an effective method in screening breast cancer.

About this research paper

What this paper is about

Objective To investigate the clinical value of detecting five serum markers:CA15-3,CA125,CEA,CYFRA21-1 and TPS in different combination for diagnosis of breast cancer.Methods The five serum markers were detected by enzyme linked immunosorbent assay in 48 cases of breast cancer and 20 cases of benign breast diseases.Results The levels and the positive rates of the five serum markers in breast cancer patients were significantly higher than those of benign breast disease patients.The sensitivity of breast cancer by detecting the five serum markers respectively was 54.2%,47.9%,29.1%,43.75% and 31.25%,and that was 87.5% by CA15-3 plus CA125.Conclusion The serum markers--CA125,CA15-3 and CYFRA21-1 were much more sensitive markers,and the combined detection of CA125 and CA15-3 was an effective method in screening breast cancer.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate the clinical value of detecting five serum markers:CA15-3,CA125,CEA,CYFRA21-1 and TPS in different combination for diagnosis of breast cancer.Methods The five serum markers were detected by enzyme linked immunosorbent assay in 48 cases of breast cancer and 20 cases of benign breast diseases.Results The levels and the positive rates of the five serum markers in breast cancer patients were significantly higher than those of benign breast disease patients.The sensitivity of breast cancer by detecting the five serum markers respectively was 54.2%,47.9%,29.1%,43.75% and 31.25%,and that was 87.5% by CA15-3 plus CA125.Conclusion The serum markers--CA125,CA15-3 and CYFRA21-1 were much more sensitive markers,and the combined detection of CA125 and CA15-3 was an effective method in screening breast cancer.

Key concepts: Breast cancer, Medicine, CA15-3, Internal medicine, CA 15-3, Breast disease, Oncology, Cancer

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Clinical significance of five serum markers in diagnosis of breast cancer — Research Paper | ScholarLens