Effect observation of different therapeutic regimens on corneal edema in grade II-III after small-incision cataract surgery

Objective To explore the clinical therapeutic effect of corneal edema in grade Ⅱ-Ⅲ after small-incision cataract surgery. Methods 340 cases of patients(400 eyes) suffered from corneal edema in grade Ⅱ-Ⅲ after cataract surgery in our hospital from June 2009 to February 2014 were randomly divided into observation group and control group.In the observation group,10 ml 10% sodium chloride solution,5 mg dexamethasone(1 ml),and 500 mg vitamin C were mixed for atomization sparging eyes.10% sodium chloride solution was put into empty bottle of chloramphenicol eye drops for eye drops four times per day.Tobramycin and dexamethasone eye drop was also used for eye drops every30 min per drip.Tetracycline cortisone eye ointment was painted for eyes before sleep every night.In the control group,only tobramycin and dexamethasone eye drop which was also used for eye drops(every 30 min per drip) and tetracycline cortisone eye ointment which was painted for eyes before sleep every night were selected.Patients in both groups were discharged from hospital and classified into outpatient follow-up observation when corneal edema turned into grade Ⅰ. Results Postoperative improvement rate in the third day in patients with corneal edema in grade Ⅱ in the observation group was higher than that in the control group,the difference was significant(χ2=42.63,P=0.0000).The cure rate in the 7th day in patients with corneal edema in grade Ⅱ in the observation group was higher than that in the control group,the difference was significant(χ2=98.05,P=0.0000).Postoperative improvement rate in the 3rdand 7thday in patients with corneal edema in grade Ⅲ in the observation group was higher than that in the control group,the difference was significant(χ2=37.62,8.95,P =0.0000). Conclusion The drugs used for corneal edema in grade Ⅱ-Ⅲ after small-incision cataract surgery are very common and their therapeutic effects are very obvious.The therapeutic regimen in the observation group is worthy of expansion in the activity of cataract supporting the poor and regaining the sight.