Comparison of the efficacy between pioglitazone and metformin in the treatment of patients with type 2 diabetes patients

Objective To compare the efficacy between pioglitazone and metformin in the treatment of patients with type 2 diabetes.Methods Ninety-six petients with type 2 diabetes were divided into a control group and a treatment group based on treatment order,each group had 48 patients.The control group were treated with metformin;the treatment group were treated with pioglitazone.One month after treatment,the control conditions of blood glucose were compared between two groups.Results After one month of the medication,the total effective rate of control group was 87.5%(42/48),that of the treatment group was 89.6%(43/48),there was no statistically significant difference between two groups(P0.05).In treatment group,the fasting plasma glucose and 2 h postprandial blood sugar level improved slightly larger than the control group(P0.05);the incidence of adverse reactions of the control group was more than that of treatment group(P0.01).Conclusion Metformin,pioglitazone can effectively control blood glucose of patients with type 2 diabetes.