2010Zhōnghuá yàoxué zázhìRequires access

Study on Chemical Constituents of Urena procumbens L.

De‐Yun Kong

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Abstract

OBJECTIVE To investigate the chemical constituents in Urena lobata L.METHODS The herbal medicine was extracted by different solvents and the constituents were separated by chromatography on silica gel,Sephadex LH-20,MCI gel,and ODS column.Their structures were determined by MS and NMR assay.RESULTS Eleven compounds of Urena lobata L.were isolated and identified as: scopoletin(1),fraxitin(2),caprolactam(3),bis(2-methylproyl) ester(4),6-C-β-L-rhamnosylopigenin(5),6,8-dihydroxy kaempferol-3-O-β-D-glycoside(6),baicalein-7-O-α-L-rhamnoside(7),quercetin-4′-O-α-L-rhamnosyl(1→6)-O-β-D-glycoside(8),benzoic acid(9),esculin(10) and glucosyringic acid(11).CONCLUSION All compounds are isolated from Urena lobata L.for the first time.

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OBJECTIVE To investigate the chemical constituents in Urena lobata L.METHODS The herbal medicine was extracted by different solvents and the constituents were separated by chromatography on silica gel,Sephadex LH-20,MCI gel,and ODS column.Their structures were determined by MS and NMR assay.RESULTS Eleven compounds of Urena lobata L.were isolated and identified as: scopoletin(1),fraxitin(2),caprolactam(3),bis(2-methylproyl) ester(4),6-C-β-L-rhamnosylopigenin(5),6,8-dihydroxy kaempferol-3-O-β-D-glycoside(6),baicalein-7-O-α-L-rhamnoside(7),quercetin-4′-O-α-L-rhamnosyl(1→6)-O-β-D-glycoside(8),benzoic acid(9),esculin(10) and glucosyringic acid(11).CONCLUSION All compounds are isolated from Urena lobata L.for the first time.

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Available abstract

OBJECTIVE To investigate the chemical constituents in Urena lobata L.METHODS The herbal medicine was extracted by different solvents and the constituents were separated by chromatography on silica gel,Sephadex LH-20,MCI gel,and ODS column.Their structures were determined by MS and NMR assay.RESULTS Eleven compounds of Urena lobata L.were isolated and identified as: scopoletin(1),fraxitin(2),caprolactam(3),bis(2-methylproyl) ester(4),6-C-β-L-rhamnosylopigenin(5),6,8-dihydroxy kaempferol-3-O-β-D-glycoside(6),baicalein-7-O-α-L-rhamnoside(7),quercetin-4′-O-α-L-rhamnosyl(1→6)-O-β-D-glycoside(8),benzoic acid(9),esculin(10) and glucosyringic acid(11).CONCLUSION All compounds are isolated from Urena lobata L.for the first time.

Key concepts: Chromatography, Sephadex, Glycoside, Chemistry, Silica gel, Kaempferol, Column chromatography, Scopoletin

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