Clinical effect of rhubarb combined with sodium sulfate on gastrointestinal dysfunction in critical care patients

[Objective] To observe the protective and treatment effects of rhubarb combined with sodium sulfate in critical care patients with gastrointestinal dysfunction.[Methods] The enrolled patients in the study had digestive disorders and APACHE Ⅱ≥16 scores and the patients with organic gastrointestinal diseases were excluded.In treatment group: the 50 mg of crude rhubarb was inserted in 100 mL of water at 100 ℃ for 15 minutes till dark brown was found.After that the drug was infused into the treatment patients by stomach tube feeding slowly,3 times a day.At the same time 100 g of sodium sulfate in double dressing package was flatly masked on belly button,changed a time when the gauze bag became wet and changed 2~3 times a day.In control group: 10 mg of mosanpride tablets was given by nasal feeding,3 times a day.The time of abdominal distension relieving,time of beginning to defecate,time of starting enteral nutrition and the incidence of gastrointestinal bleeding were observed in both groups.[Results] In treatment group the time of abdominal distension relieving,the time of smoothly starting enteral nutrition and defecate time were shorter than that in control group(P0.05 or P0.01).Incidence of gastrointestinal bleeding in treatment group was also significantly lower than that in control group.[Conclusion] Rhubarb combined with sodium sulfate can significantly protect the patients with gastrointestinal dysfunction in critical care,reduce the incidence of gastrointestinal bleeding and ameliorate the prognosis of patients.