Reactive results of Treponema pallidum antibody in chemiluminescent assay

Objective To find the cause of false positive results during the detection of Treponema pallidum antibody(TP) in chemiluminescent assay.Methods We put 129 TP reactive samples to chemiluminscent assay,reexamined them by treponema pallidum hemaglutination assay(TPHA) before comparing them.Results When cut - off S/CO was 1,the difference was significant,but there was no significant difference when cut - off S/CO was 5.Conclusions When anti - TP is reactive,especially in the samples of low S/CO value(1.0-5.0),multiple factors should be taken into consideration,such as age,history of disease,and clinical symptoms, followed by re - examination of the sample by other means.In this way,the chance of false positivity will be reduced.