2012Journal of Tropical MedicineOpen access

Using the high sensitivity c-reactive protein and urinary tract infection information in the diagnosis of urinary tract infection

Rong Qi

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Abstract

Objective To evaluate the application value of using the high sensitivity c-reactive protein(hs-CRP) and urinary tract infection information(UTI-Info) in diagnosis of urinary tract infection(UTI).Methods 380 urine specimens from suspected UTI patients were cultured for bacterial identification.UF-1000i automated urine analyzer was used to detect white blood cell count(WBC) and bacterial count(BACT).AU2700 automatic biochemistry analyzer was used to detect hs-CRP in venous blood.Bacterial cell count was used as standard for the evaluation of sensitivity,specificity and diagnostic accordance rate of hs-CRP,UTI-Info and hs-CRP+UTI-Info.Results Except the contaminated samples,102 out of 360 samples(28.3%) were positive for bacterial growth.The sensitivity,specificity and diagnostic accordance rate of hs-CRP in the diagnosis of UTI were 85.3%,70.9% and 75.0%,respectively.The sensitivity,specificity and diagnostic accordance rate of UTI-Info in the diagnosis of UTI were 76.5%,84.5% and 82.2%,respectively.The sensitivity,specificity and diagnostic accordance rate of hs-CRP+UTI-Info in the diagnosis of UTI were 70.6%,97.3% and 89.7%,respectively.Conclusion The combination of hsCRP and UTI-Info can be used for the fast and specific diagnosis of UTI.

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Objective To evaluate the application value of using the high sensitivity c-reactive protein(hs-CRP) and urinary tract infection information(UTI-Info) in diagnosis of urinary tract infection(UTI).Methods 380 urine specimens from suspected UTI patients were cultured for bacterial identification.UF-1000i automated urine analyzer was used to detect white blood cell count(WBC) and bacterial count(BACT).AU2700 automatic biochemistry analyzer was used to detect hs-CRP in venous blood.Bacterial cell count was used as standard for the evaluation of sensitivity,specificity and diagnostic accordance rate of hs-CRP,UTI-Info and hs-CRP+UTI-Info.Results Except the contaminated samples,102 out of 360 samples(28.3%) were positive for bacterial growth.The sensitivity,specificity and diagnostic accordance rate of hs-CRP in the diagnosis of UTI were 85.3%,70.9% and 75.0%,respectively.The sensitivity,specificity and diagnostic accordance rate of UTI-Info in the diagnosis of UTI were 76.5%,84.5% and 82.2%,respectively.The sensitivity,specificity and diagnostic accordance rate of hs-CRP+UTI-Info in the diagnosis of UTI were 70.6%,97.3% and 89.7%,respectively.Conclusion The combination of hsCRP and UTI-Info can be used for the fast and specific diagnosis of UTI.

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Available abstract

Objective To evaluate the application value of using the high sensitivity c-reactive protein(hs-CRP) and urinary tract infection information(UTI-Info) in diagnosis of urinary tract infection(UTI).Methods 380 urine specimens from suspected UTI patients were cultured for bacterial identification.UF-1000i automated urine analyzer was used to detect white blood cell count(WBC) and bacterial count(BACT).AU2700 automatic biochemistry analyzer was used to detect hs-CRP in venous blood.Bacterial cell count was used as standard for the evaluation of sensitivity,specificity and diagnostic accordance rate of hs-CRP,UTI-Info and hs-CRP+UTI-Info.Results Except the contaminated samples,102 out of 360 samples(28.3%) were positive for bacterial growth.The sensitivity,specificity and diagnostic accordance rate of hs-CRP in the diagnosis of UTI were 85.3%,70.9% and 75.0%,respectively.The sensitivity,specificity and diagnostic accordance rate of UTI-Info in the diagnosis of UTI were 76.5%,84.5% and 82.2%,respectively.The sensitivity,specificity and diagnostic accordance rate of hs-CRP+UTI-Info in the diagnosis of UTI were 70.6%,97.3% and 89.7%,respectively.Conclusion The combination of hsCRP and UTI-Info can be used for the fast and specific diagnosis of UTI.

Key concepts: Medicine, Urine, Urinary system, C-reactive protein, White blood cell, Internal medicine, Gastroenterology, Inflammation

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