Clinical Observation of Unruptured Ectopic Pregnancy Treated by Mifepristone and MTX

Objective To explore effect of different doses of mifepristone combined with MTX treatment of unruptured ectopic pregnancy.Method Retrospective analysis from March 2005 to August 2009 in Nanwan hospital from different conservative treatment programs in patients with un-ruptured ectopic pregnancy 156 cases,Summary analysis of different doses of mifepristone and MTX combination therapy of conservative treatment.Result Larger doses of mifepristone combined treatment group of cure rate is significantly higher than small doses combined treatment and single use MTX therapy two groups,Comparison difference statistically significance(P0.01),Small doses of mifepristone treatment,the cure rates higher than the single treatment group with MTX,Comparison difference statistically significance(P0.05),About drug side effects,MTX dose increases with bone marrow suppression,Increase the dose of mifepristone was no significant difference in side effects,No statistical significance(P0.05).Conclusion Larger doses of mifepristone combined with MTX treatment of unruptured ectopic pregnancy,can effectively improve effectiveness,and does not increase adverse drug reactions.