Clinical Study on Santeng Tongbi Pills in Treating 53 Cases of Rheumatoid Arthritis

Objective To observe the clinical efficacy of Santeng Tongbi pills on rheumatoid arthritis (RA),evaluate the safety and explore its mechanism. Methods Double-blind and double dummy design method was used. 107 cases of RA were randomly divided into Santeng Tongbi pills group (the treatment group,53 cases) and Zhengqing Fengtongning group (the control group,54 cases). The Ritchie index,health assessment questionnaire (HAQ),arthritis influenced index (AIMS),patinents' assessment to pain (VAS form),acute phase reactant,Chinese medical pattern grade,the hemorheology state and so on were retrospectively analyzed. Results There was significantly difference between RA patients and healthy people on the hemorheology state (P 0.05). The total effective rate in the two groups were 88.68% and 68.52% respectively,the treatment group was better than the control group (P 0.01). After two courses of treatment,the two groups were developed obviously on Ritchit index,HAQ,AIMS,patinents' assessment to pain,acute phase reactant,Chinese medical pattern grade,the hemorheology state etc (P0.05 or P 0.01). The treatment group was better than the control group after the treatment (P 0.05 or P 0.01). Conclusion It was thick,sticky,compact state in blood of RA patients. Santeng Tongbi pills can develop the hemorheology state and improve the joint movement and the quality of life of RA patients.