Efficacy of simvastatin on acute coronary syndrome in 120 cases

Objective To investigate the clinical efficacy of simvastatin on acute coronary syndrome (ACS). Methods Altogether 120 patients with ACS were randomly divided into treatment group ( n = 60) and control group ( n = 60). Patients in treatment group received 20 mg simvastatin per night on the basis of conventional treatment. And patients in control group received conventional treatment only. Two months later the serum lipid levels and re-admission incidence were observed. Results In treatment group,the levels of triglyceride,cholesterol,lowdensity lipoprotein and high sensitive-C reactive protein decreased markedly and highdensity lipoprotein increased significantly compared with which before treatment ( P 0. 05). There was no statistical difference on the levels of serum lipid post treatment in patients of conventional treatment. There was statistical difference on re-admission incidence for myocardial ischemia between treatment group and control group ( P 0. 05). Conclusion Simvastatin is capable of regulating lipid and decreasing re-admission incidence in acute coronary syndrome.