Detection of coronary artery stenosis using 64-slice spiral CT compared with catheter coronary angiography

Objective To evaluate the accuracy of 64-slice spiral CT angiography (MSCT) in detecting coronary artery stenosis and its clinical application. Methods Sixty-nine patients with known or suspected coronary artery disease underwent both spiral CT coronary arteriography and catheter coronary angiography. Vessel diameter reduction 50% was defined as significant stenosis. Results A 98.7% (778/788) of the coronary artery segments (vessel diameter ≥1.5 mm) could be visualized by 64-slice spiral CT. Compared with catheter angiography in the detection of coronary stenosis, the overall sensitivity, specificity, positive predictive value, negative predictive value and the accuracy of 64-slice CT coronary angiography were 81.9%, 99.0%, 95.9%, 95.1%, and 95.2% respectively. Overall sensitivity would be 91.8% if corrected methodologically. The sensitivity after methodological correction became 91.8%. Conclusion Sixty-four-slice spiral CT examiniation provides a promising non-invasive approach in detecting coronary stenosis with fairly good accuracy, but can not totally replace catheter coronary angiography yet.