Propyl Gallate on Hemolysis and Osmotic Fragility of Red Blood Cells

Objective To research whether the propyl gallate can influence the hemolysis and osmotic fragility of red blood cells. Methods Different concentrations of propyl gallate ( 256 μg/ml, 128 μg/ml, 64 μg/ml, 32 μg/ml, 16 μg/ml, 8 μg/ml) were incubated with red blood cells for 12 hours. The levels of hemolysis were detected by visual observation and hemiglobincyanide; The red blood cell osmotic fragility test was used to detected the maximum and minimum osmotic fragility. The hemiglobincyanide was also used to detect the hemolytic status of maximum osmotic fragility. The statistical software SPSS 16.0 was applied to analyze the results. Results No significant hemolysis was observed by eyes. There were no conspicuous differences of the maximum and minimum osmotic fragility among the experimental groups, the control group and the reference value of health adults. When comparing the hemolysis of the the maximum osmotic fragility, there were no significant differences (P 0.05). Conclusion Propyl gallate can't influence the hemolysis and osmotic fragility of red blood cells.