Clinical Curative Effect Comparison of Fluconazole Versus Nystatin Combined with Sodium Bicarbonate in the Treatment of 44 Cases Pediatric Thrush

Objective: To observe clinical curative effect the fluconazole versus nystatin combine with sodium bicarbonate injection in treatment of infant thrush,for clinical treatment of thrush drug selection guide. Method: 88 cases of thrush were randomly divided into two groups,fluconazole group using fluconazole capsule(5mg / kg.d,once a day,after lunch,clothing),nystatin nystatin group combined with sodium bicarbonate injection(2.5% sodium bicarbonate solution of oral care,oral nystatin levigation smear),5 days later comparison of two group effect,oral signs to improve the situation. Result: Total effective rate was fluconazole treatment group 88.63%,total effective rate was 84.09% in nystatin treatment group,statistical analysis showed no significant differences between the two groups.(P 0.05). Conclusion: Fluconazole versus nystatin combined with sodium bicarbonate injection in the treatment of oral thrush similar results,according to the patients economic conditions,adverse reactions,drug resistance,comfort and other specific circumstances to choose medicine.