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2015•Zhongguo bijiao yixue zazhiRequires access

Oxidative stress and renal cell apoptosis

Fu Bing Huang

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Abstract

Reactive oxygen species( ROS) resulting from oxidative stress have a close relationship with cell apoptosis. ROS induces cell apoptosis through activating different signaling pathways including mitochondria,Bcl-2,NF-κB,MAPKSand Caspases and so on. Cell apoptosis plays a significant role in the course of kidney diseases. In this paper,the function of oxidative stress in the development and progression of kidney diseases and apoptosis mechanism induced by oxidative stress are reviewed.

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What this paper is about

Reactive oxygen species( ROS) resulting from oxidative stress have a close relationship with cell apoptosis. ROS induces cell apoptosis through activating different signaling pathways including mitochondria,Bcl-2,NF-κB,MAPKSand Caspases and so on. Cell apoptosis plays a significant role in the course of kidney diseases. In this paper,the function of oxidative stress in the development and progression of kidney diseases and apoptosis mechanism induced by oxidative stress are reviewed.

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OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Reactive oxygen species( ROS) resulting from oxidative stress have a close relationship with cell apoptosis. ROS induces cell apoptosis through activating different signaling pathways including mitochondria,Bcl-2,NF-κB,MAPKSand Caspases and so on. Cell apoptosis plays a significant role in the course of kidney diseases. In this paper,the function of oxidative stress in the development and progression of kidney diseases and apoptosis mechanism induced by oxidative stress are reviewed.

Key concepts: Oxidative stress, Apoptosis, Reactive oxygen species, Cell biology, Mitochondrion, Caspase, Cell, Oxidative phosphorylation

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