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Analysis on the results of 50g GCT and 75g OGTT of 137 cases with GDM

Yang Su-an

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Abstract

[Objective] To explore the effects of diagnostic criteria and time of 50g GCT and 75g GOTT in patients with gastational diabetes mellitus (GDM) on pregnancy outcome. [Methods] Clinical data and results of 50g GCT and 75g GOTT of 137 patients with GDM of People's Hospital of Peking University were retrospected. [Results] The missed diagnostic rate was about 5.19% if the cut-off value of 50g GCT was 7.2 mmol/L; the average fasting plasma glucose (FPG) of 75g GOTT was (4.95±1.20) mmol/L, 1h postprandial plasma glucose (1hPG) was (11.08±1.76) mmol/L, 2 h postprandial plasma glucose (2hPG) was (9.46±2.65) mmol/L, 3 h postprandial plasma glucose (3hPG) was (6.39±2.32) mmol/L; 21 cases of GDM, about 16.3%, would be missed diagnosed if 3hPG of 75g OGTT was not tested; obvious overweight of neonate would be diagnosed after gestational 36 weeks. [Conclusion] FPG value of 75g GOTT in patients with GDM is considered to be decreased, while 1hPG and 2hPG values increase. 3hPG of 75g OGTT should no be omitted. GDM should be early screened and diagnosed so that the patient could be treated early and the prognosis would be improved.

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What this paper is about

[Objective] To explore the effects of diagnostic criteria and time of 50g GCT and 75g GOTT in patients with gastational diabetes mellitus (GDM) on pregnancy outcome. [Methods] Clinical data and results of 50g GCT and 75g GOTT of 137 patients with GDM of People's Hospital of Peking University were retrospected. [Results] The missed diagnostic rate was about 5.19% if the cut-off value of 50g GCT was 7.2 mmol/L; the average fasting plasma glucose (FPG) of 75g GOTT was (4.95±1.20) mmol/L, 1h postprandial plasma glucose (1hPG) was (11.08±1.76) mmol/L, 2 h postprandial plasma glucose (2hPG) was (9.46±2.65) mmol/L, 3 h postprandial plasma glucose (3hPG) was (6.39±2.32) mmol/L; 21 cases of GDM, about 16.3%, would be missed diagnosed if 3hPG of 75g OGTT was not tested; obvious overweight of neonate would be diagnosed after gestational 36 weeks. [Conclusion] FPG value of 75g GOTT in patients with GDM is considered to be decreased, while 1hPG and 2hPG values increase. 3hPG of 75g OGTT should no be omitted. GDM should be early screened and diagnosed so that the patient could be treated early and the prognosis would be improved.

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Available abstract

[Objective] To explore the effects of diagnostic criteria and time of 50g GCT and 75g GOTT in patients with gastational diabetes mellitus (GDM) on pregnancy outcome. [Methods] Clinical data and results of 50g GCT and 75g GOTT of 137 patients with GDM of People's Hospital of Peking University were retrospected. [Results] The missed diagnostic rate was about 5.19% if the cut-off value of 50g GCT was 7.2 mmol/L; the average fasting plasma glucose (FPG) of 75g GOTT was (4.95±1.20) mmol/L, 1h postprandial plasma glucose (1hPG) was (11.08±1.76) mmol/L, 2 h postprandial plasma glucose (2hPG) was (9.46±2.65) mmol/L, 3 h postprandial plasma glucose (3hPG) was (6.39±2.32) mmol/L; 21 cases of GDM, about 16.3%, would be missed diagnosed if 3hPG of 75g OGTT was not tested; obvious overweight of neonate would be diagnosed after gestational 36 weeks. [Conclusion] FPG value of 75g GOTT in patients with GDM is considered to be decreased, while 1hPG and 2hPG values increase. 3hPG of 75g OGTT should no be omitted. GDM should be early screened and diagnosed so that the patient could be treated early and the prognosis would be improved.

Key concepts: Postprandial, Medicine, Gestational diabetes, Plasma glucose, Internal medicine, Overweight, Diabetes mellitus, Pregnancy

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Analysis on the results of 50g GCT and 75g OGTT of 137 cases with GDM — Research Paper | ScholarLens