ScholarLens Back to search
2010•Chinese Journal of PharmacovigilanceRequires access

Determination of Isofraxidin in Medofenoxate Fruits by HPLC

Junyi Zhu

Open publisher page 0 citations

Abstract

Objective To establish a HPLC method for the determination of isofraxidin in medofenoxate fruits.Methods Agilent XDB C18(4.6 mm×150 mm,5μm) column was applied,using methanol-0.2% phosphoric acid (27:73)as mobile phase with the rate of 1.0mL·min-1.The column temperature was room temperature,the injection volumn was 10μL and the detective wavelength was 343 nm.Results A good linearity was obtained over the range of 0.835～4.176μg·mL-1 for isofraxidin(r=0.9996).The average recovery(n=6) was 100.74%(RSD=0.44%).Conclusion The method is practical,convenient,accurate,and can be used as the determination of isofraxidin in medofenoxate fruits.

About this research paper

What this paper is about

Objective To establish a HPLC method for the determination of isofraxidin in medofenoxate fruits.Methods Agilent XDB C18(4.6 mm×150 mm,5μm) column was applied,using methanol-0.2% phosphoric acid (27:73)as mobile phase with the rate of 1.0mL·min-1.The column temperature was room temperature,the injection volumn was 10μL and the detective wavelength was 343 nm.Results A good linearity was obtained over the range of 0.835～4.176μg·mL-1 for isofraxidin(r=0.9996).The average recovery(n=6) was 100.74%(RSD=0.44%).Conclusion The method is practical,convenient,accurate,and can be used as the determination of isofraxidin in medofenoxate fruits.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To establish a HPLC method for the determination of isofraxidin in medofenoxate fruits.Methods Agilent XDB C18(4.6 mm×150 mm,5μm) column was applied,using methanol-0.2% phosphoric acid (27:73)as mobile phase with the rate of 1.0mL·min-1.The column temperature was room temperature,the injection volumn was 10μL and the detective wavelength was 343 nm.Results A good linearity was obtained over the range of 0.835～4.176μg·mL-1 for isofraxidin(r=0.9996).The average recovery(n=6) was 100.74%(RSD=0.44%).Conclusion The method is practical,convenient,accurate,and can be used as the determination of isofraxidin in medofenoxate fruits.

Key concepts: Phosphoric acid, Chromatography, High-performance liquid chromatography, Chemistry, Methanol, Recovery rate, Organic chemistry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Determination of Isofraxidin in Medofenoxate Fruits by HPLC — Research Paper | ScholarLens