Study on the clinical efficacy and safety of aerosol inhalation of salbutamol combined with budesonide for treatment of pediatric asthma

Objective:To explore the clinical efficacy and safety of aerosol inhalation of salbutamol combined with budesonide for treatment of pediatric asthma.Methods:The clinical data of 82 infants with bronchial asthma who were treated in the hospital from January 2011 to January 2012 were analyzed retrospectively;the clinical efficacies and adverse reactions in observation group(aerosol inhalation of salbutamol combined with budesonide) and control group(aerosol inhalation of salbutamol) were observed,compared,and analyzed.Results:The total effective rate in observation group was 95.12%,which was statistically significantly higher than that in control group(78.05%)(P0.05);The disappearance time of symptoms and mean hospitalization time in observation group were statistically significantly lower than those in control group(P0.01);the improvement of pulmonary function in observation group was better than that in control group(P0.05);the adverse reactions in the two groups were mild.Conclusion:Aerosol inhalation of salbutamol combined with budesonide has the advantages of good curative effect,fast effect,obvious improvement of symptoms,and less adverse reactions,which can be used as a good therapeutic schedule for treatment of pediatric asthma currently.