2012•Xiandai shengwu yixue jinzhanRequires access

The Serum Cystatin-C and Urinary NGAL Levels and its Clinical Significance of Acute Kidney Injury the Patients of Acute Kidney Injury

Yong Wu

Open publisher page 0 citations

Abstract

Objective: To observe the serum cystatin-C(CysC) and the urinary neutrophil gelatinase-associated lipocalin(NGAL) level of the patients of the acute kidney injury(AKI) and to assess its clinical significance.Methods: We chose 60 patients of AKI as the experimental group,and 50 healthy people as thecontrol group.The serum cystatin-C and urinary NGAL levels of two groups were detected by enzyme-linked immunosorbent assay.Results: Compared with the control group,theserum cystatin-C and urinary NGAL levels significantly increased,and the differences were statistically significant(P 0.05).The urinary NGAL detection rate was higher than serum cystatin-C,serum creatinine of experimental group,and the difference was statistically significant(P 0.05).Conclusion: Theserum cystatin-C and urinary NGAL of the patients of AKI were both increased,and the urinary NGAL was a more sensitive than the serum cystatin-C,and it is worthy studying further.

About this research paper

What this paper is about

Objective: To observe the serum cystatin-C(CysC) and the urinary neutrophil gelatinase-associated lipocalin(NGAL) level of the patients of the acute kidney injury(AKI) and to assess its clinical significance.Methods: We chose 60 patients of AKI as the experimental group,and 50 healthy people as thecontrol group.The serum cystatin-C and urinary NGAL levels of two groups were detected by enzyme-linked immunosorbent assay.Results: Compared with the control group,theserum cystatin-C and urinary NGAL levels significantly increased,and the differences were statistically significant(P 0.05).The urinary NGAL detection rate was higher than serum cystatin-C,serum creatinine of experimental group,and the difference was statistically significant(P 0.05).Conclusion: Theserum cystatin-C and urinary NGAL of the patients of AKI were both increased,and the urinary NGAL was a more sensitive than the serum cystatin-C,and it is worthy studying further.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective: To observe the serum cystatin-C(CysC) and the urinary neutrophil gelatinase-associated lipocalin(NGAL) level of the patients of the acute kidney injury(AKI) and to assess its clinical significance.Methods: We chose 60 patients of AKI as the experimental group,and 50 healthy people as thecontrol group.The serum cystatin-C and urinary NGAL levels of two groups were detected by enzyme-linked immunosorbent assay.Results: Compared with the control group,theserum cystatin-C and urinary NGAL levels significantly increased,and the differences were statistically significant(P 0.05).The urinary NGAL detection rate was higher than serum cystatin-C,serum creatinine of experimental group,and the difference was statistically significant(P 0.05).Conclusion: Theserum cystatin-C and urinary NGAL of the patients of AKI were both increased,and the urinary NGAL was a more sensitive than the serum cystatin-C,and it is worthy studying further.

Key concepts: Cystatin C, Lipocalin, Urinary system, Medicine, Acute kidney injury, Creatinine, Urology, Cystatin

Related papers

Back to paper searchBrowse research topicsOriginal source
The Serum Cystatin-C and Urinary NGAL Levels and its Clinical Significance of Acute Kidney Injury the Patients of Acute Kidney Injury — Research Paper | ScholarLens