The Serum Cystatin-C and Urinary NGAL Levels and its Clinical Significance of Acute Kidney Injury the Patients of Acute Kidney Injury
Yong Wu
Abstract
Yong Wu
Abstract
Objective: To observe the serum cystatin-C(CysC) and the urinary neutrophil gelatinase-associated lipocalin(NGAL) level of the patients of the acute kidney injury(AKI) and to assess its clinical significance.Methods: We chose 60 patients of AKI as the experimental group,and 50 healthy people as thecontrol group.The serum cystatin-C and urinary NGAL levels of two groups were detected by enzyme-linked immunosorbent assay.Results: Compared with the control group,theserum cystatin-C and urinary NGAL levels significantly increased,and the differences were statistically significant(P 0.05).The urinary NGAL detection rate was higher than serum cystatin-C,serum creatinine of experimental group,and the difference was statistically significant(P 0.05).Conclusion: Theserum cystatin-C and urinary NGAL of the patients of AKI were both increased,and the urinary NGAL was a more sensitive than the serum cystatin-C,and it is worthy studying further.
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Objective: To observe the serum cystatin-C(CysC) and the urinary neutrophil gelatinase-associated lipocalin(NGAL) level of the patients of the acute kidney injury(AKI) and to assess its clinical significance.Methods: We chose 60 patients of AKI as the experimental group,and 50 healthy people as thecontrol group.The serum cystatin-C and urinary NGAL levels of two groups were detected by enzyme-linked immunosorbent assay.Results: Compared with the control group,theserum cystatin-C and urinary NGAL levels significantly increased,and the differences were statistically significant(P 0.05).The urinary NGAL detection rate was higher than serum cystatin-C,serum creatinine of experimental group,and the difference was statistically significant(P 0.05).Conclusion: Theserum cystatin-C and urinary NGAL of the patients of AKI were both increased,and the urinary NGAL was a more sensitive than the serum cystatin-C,and it is worthy studying further.
Key concepts: Cystatin C, Lipocalin, Urinary system, Medicine, Acute kidney injury, Creatinine, Urology, Cystatin