The Clinical Study of In Vitro Fertilization and Embryo Transfer

We have reviewed 35 cycles in 27 patients who underwent IVF and ET with reasonable indications from March 1992 to February 1993. The method of ovarian hyperstimulation were FSH/hMG/hCG(N=10), GnRH agonist(N=24), C.C./hMG/hCG(N=1).The results were as follows ;1) The mean age of patients was 33.04±4.17 and mean duration of infertility was 5.52±3.37 years.2) Major indications for IVF and ET were tubal factor(77.80%), peritoneal factor(18.50%), and unexplained infertility(3.70%).3) In the past history of patients, there were previous ectopic pregnancy in 5 cases(17.24%), previous tuboplasty in 5 cases(17.24%), pevic inflammatory disease in 4 cases(16.00%), and tuberculosis in 3 cases(12.00%).4) The cancellation was only one case in FSH/hMG/hCG group.5) The timing of hCG administration in FSH/hMG/hCG group was 9.56±1.50 day and GnRH-a group was 9.17±0.99 day.6) The mean numbers of follicles larger than 16mm were 6.78±4.71 in FSH/hMG/hCG group and 5.33±3.82 in GnRH-a group.7) The mean numbers of oocyte aspirated were 6.44±3.17 in FSH/hMG/hCG group and 5.54±2.27 in GnRH-a group.8) The fertilization and cleavage rate was 59.93±33.91% in FSH/hMC/hCG group and 57.61±30.81 in GnRH-a group.9) The mean number of embryos transfered were 4.56±3.69 in FSH/hMe/hCG group and 3.38±2.10 in GnRH-a group.10) Pregnancy rate were 22.2% in FSH/hMG/hCC group and 25% in GnRH-a group.11) There were 8 cases of pregnancies which consisted of two live births of 3 babies, 3 cases of ongoing pregnancies, one spontaneous abortion, two chemical pregnancies.