1974•JNCI Journal of the National Cancer InstituteRequires access

Synthesis of Human Placental Alkaline Phosphatase in Vitro by the ChaGo Cell Line2

Marilyn A. Ludueña, Howard H. Sussman, Alan S. Rabson

Abstract

Human placental alkaline phosphatase was purified from an epithelial cell line which also synthesizes chorionic gonadotropin in vitro. The ChaGo alkaline phosphatase was immunochemically, biochemically, and functionally very similar to the alkaline phosphatase synthesized by the original tumor tissue and by normal placentas

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Key concepts: Alkaline phosphatase, Placental alkaline phosphatase, In vitro, Human chorionic gonadotropin, Phosphatase, Chemistry, Cell, Cell culture