1949New England Journal of MedicineRequires access

Use of Diethylstilbestrol to Prevent Fetal Loss from Complications of Late Pregnancy

O. Watkins Smith, George Van S. Smith

Open publisher page 60 citations

Abstract

THE present communication deals with further progress in a clinical evaluation of our concept concerning the action of diethylstilbestrol in human pregnancy. Analyses of results in 632 pregnancies during which this drug was given in the manner recommended by us have been reported.1 In 491 of these cases stilbestrol was administered for the prevention or treatment of abortion. A preliminary report was included, however, upon its use in 95 patients for the purpose of preventing complications of late pregnancy. These 95 cases are included in the present study of a total of 180 women in whom the indication for therapy . . .

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What this paper is about

THE present communication deals with further progress in a clinical evaluation of our concept concerning the action of diethylstilbestrol in human pregnancy. Analyses of results in 632 pregnancies during which this drug was given in the manner recommended by us have been reported.1 In 491 of these cases stilbestrol was administered for the prevention or treatment of abortion. A preliminary report was included, however, upon its use in 95 patients for the purpose of preventing complications of late pregnancy. These 95 cases are included in the present study of a total of 180 women in whom the indication for therapy . . .

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OpenAlex reports 60 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

THE present communication deals with further progress in a clinical evaluation of our concept concerning the action of diethylstilbestrol in human pregnancy. Analyses of results in 632 pregnancies during which this drug was given in the manner recommended by us have been reported.1 In 491 of these cases stilbestrol was administered for the prevention or treatment of abortion. A preliminary report was included, however, upon its use in 95 patients for the purpose of preventing complications of late pregnancy. These 95 cases are included in the present study of a total of 180 women in whom the indication for therapy . . .

Key concepts: Medicine, Diethylstilbestrol, Stilbestrol, Pregnancy, Abortion, Obstetrics, Fetus, Gynecology

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