2010•Zhonghua zhongyiyao xuekanRequires access

Study on the extraction process of total flavonoids from Chrysanthemum morifolium Ramat and its kinetics.

Xiao-Xia Zhou

Abstract

Objective:To investigate the best extracting process of total flavonoids from Chrysanthemum morifolium Ramat and its kinetics.Methods:The single-factor analysis was employed to optimize the degree of grinding,ratio of water to raw material,extraction time and extraction temperature to obtain a high total flavonoids yield.Results:The optimum conditions were a ratio of 70% ethanol to raw material of 40 mL/g and extraction time 2.25 h at 80°C.Extraction process was followed as the model ln(Vs-V)=-1.8789t+0.8342(r=0.9957).Conclusion:The method would be useful for the process design and the choice of operation condition to extract flavonoids from Chrysanthemum morifolium Ramat.

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Key concepts: Chrysanthemum morifolium, Extraction (chemistry), Raw material, Yield (engineering), Chemistry, Grinding, Chromatography, Botany