Mycoplasma Infection and Drug Susceptivity in Outpatients with Nongonococcal Urethritis

OBJECTIVE To investigate the infection and drug resistance of mycoplasma in outpatients with nongonococcal urethritis(NGU),to provide bases for the rational application of antibiotics.METHODS Mycoplasma IST2 kits were used to isolate mycoplasma and drug susceptibility was detected with mycoplasma positive specimens.RESULTS Form 2159 specimens 1212 were positive for mycoplasma,the positive rate was 56.2%.The positive rate of Ureaplasma urealyticum(Uu) and Mycoplasma hominis(Mh) were 38.0% and 2.6%,respectively,and the mixed infection rate was 15.6%.Among 9 commonly employed antibiotics,Mycoplasma were susceptible to pristinamycin,doxycycline and tetracycline in turn,and severely resistant to ciprofloxacin and ofloxacin.CONCLUSION Mycoplasma(especially Uu) are the main pathogens of NGU.It is important to isolate mycoplasma and test their drug susceptibility with NGU patients.Pristinamycin,doxycycline and tetracycline are the first choice for the NGU patients in this area.