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ANTIOXIDANT POTENTIAL OF CLERODENDRON VISCOSUM VENT. ROOTS

P. Pankaj, V.B. Narayanasamy, Manjunath M Setty, Annie Shirwaikar

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Abstract

Summary The free radical scavenging potential of the roots of C. viscosum was studied by using different antioxidant models of screening. The ethanolic extract at 1000 µg/ml showed maximum scavenging of the radical cation, 2,2-azinobis-(3-ethylbenzothiazoline-6sulphonate)(ABTS) observed upto 98.92% followed by scavenging of nitric oxide radical (96.75%), ferric ion radical (94.43%), 1,1- diphenyl, 2-picryl hydrazyl (DPPH) (92.25%) and antilipid peroxidation potential (81.13%) The aqueous extract showed only moderate activity. The finding justifies the therapeutic application of the plant in the indigenous system of medicine, augmenting its therapeutic value.

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Summary The free radical scavenging potential of the roots of C. viscosum was studied by using different antioxidant models of screening. The ethanolic extract at 1000 µg/ml showed maximum scavenging of the radical cation, 2,2-azinobis-(3-ethylbenzothiazoline-6sulphonate)(ABTS) observed upto 98.92% followed by scavenging of nitric oxide radical (96.75%), ferric ion radical (94.43%), 1,1- diphenyl, 2-picryl hydrazyl (DPPH) (92.25%) and antilipid peroxidation potential (81.13%) The aqueous extract showed only moderate activity. The finding justifies the therapeutic application of the plant in the indigenous system of medicine, augmenting its therapeutic value.

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Available abstract

Summary The free radical scavenging potential of the roots of C. viscosum was studied by using different antioxidant models of screening. The ethanolic extract at 1000 µg/ml showed maximum scavenging of the radical cation, 2,2-azinobis-(3-ethylbenzothiazoline-6sulphonate)(ABTS) observed upto 98.92% followed by scavenging of nitric oxide radical (96.75%), ferric ion radical (94.43%), 1,1- diphenyl, 2-picryl hydrazyl (DPPH) (92.25%) and antilipid peroxidation potential (81.13%) The aqueous extract showed only moderate activity. The finding justifies the therapeutic application of the plant in the indigenous system of medicine, augmenting its therapeutic value.

Key concepts: DPPH, Antioxidant, Scavenging, Chemistry, ABTS, Traditional medicine, Ferric, Nitric oxide

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