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[Analysis of prognostic factors of anatomical and functional results of idiopathic macular hole surgery].

Robert Kaňovský, T Jurecka, Eva Gelnarová

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Abstract

PURPOSE: Analysis of preoperative prognostic factors in idiopathic macular hole surgery and determination of their significance for the final postoperative visual functions. METHODS: Ninety-one patients with idiopathic macular hole were enrolled into this study. The best-corrected visual acuity, macular hole staging according to Gass classification and duration of macular hole symptoms were evaluated preoperatively. Pars plana vitrectomy with internal limiting membrane peeling and expanding gas (C3F8) tamponade was subsequently performed in all patients. Macular hole closure rate--anatomical success of the surgery--and visual acuity (functional results) were postoperatively assessed. RESULTS: Positive correlation between the duration of the macular hole symptoms and the final postoperative visual functions (Kruskal-Wallis; P = 0.003) as well as between the duration of the macular hole symptoms and the postoperative macular hole closure rate (Man-Whitney; P = 0.001) were found in patients with idiopathic macular holes. Postoperative significant improvement of visual acuity depends on the preoperative macular hole stage according to Gass classification (Pearsovov xhi2; P = 0.05). CONCLUSION: Macular hole symptoms duration and preoperative macular hole stage are the two significant prognostic factors for postoperative functional and anatomical results.

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PURPOSE: Analysis of preoperative prognostic factors in idiopathic macular hole surgery and determination of their significance for the final postoperative visual functions. METHODS: Ninety-one patients with idiopathic macular hole were enrolled into this study. The best-corrected visual acuity, macular hole staging according to Gass classification and duration of macular hole symptoms were evaluated preoperatively. Pars plana vitrectomy with internal limiting membrane peeling and expanding gas (C3F8) tamponade was subsequently performed in all patients. Macular hole closure rate--anatomical success of the surgery--and visual acuity (functional results) were postoperatively assessed. RESULTS: Positive correlation between the duration of the macular hole symptoms and the final postoperative visual functions (Kruskal-Wallis; P = 0.003) as well as between the duration of the macular hole symptoms and the postoperative macular hole closure rate (Man-Whitney; P = 0.001) were found in patients with idiopathic macular holes. Postoperative significant improvement of visual acuity depends on the preoperative macular hole stage according to Gass classification (Pearsovov xhi2; P = 0.05). CONCLUSION: Macular hole symptoms duration and preoperative macular hole stage are the two significant prognostic factors for postoperative functional and anatomical results.

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Available abstract

PURPOSE: Analysis of preoperative prognostic factors in idiopathic macular hole surgery and determination of their significance for the final postoperative visual functions. METHODS: Ninety-one patients with idiopathic macular hole were enrolled into this study. The best-corrected visual acuity, macular hole staging according to Gass classification and duration of macular hole symptoms were evaluated preoperatively. Pars plana vitrectomy with internal limiting membrane peeling and expanding gas (C3F8) tamponade was subsequently performed in all patients. Macular hole closure rate--anatomical success of the surgery--and visual acuity (functional results) were postoperatively assessed. RESULTS: Positive correlation between the duration of the macular hole symptoms and the final postoperative visual functions (Kruskal-Wallis; P = 0.003) as well as between the duration of the macular hole symptoms and the postoperative macular hole closure rate (Man-Whitney; P = 0.001) were found in patients with idiopathic macular holes. Postoperative significant improvement of visual acuity depends on the preoperative macular hole stage according to Gass classification (Pearsovov xhi2; P = 0.05). CONCLUSION: Macular hole symptoms duration and preoperative macular hole stage are the two significant prognostic factors for postoperative functional and anatomical results.

Key concepts: Macular hole, Vitrectomy, Medicine, Tamponade, Visual acuity, Pars plana, Ophthalmology, Internal limiting membrane

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