ChemInform Abstract: SYNTHESIS OF TRANS‐3,4‐DIHYDROXY‐3,4‐DIHYDRO‐7,12‐DIMETHYLBENZ(A)ANTHRACENE, A HIGHLY CARCINOGENIC METABOLITE OF 7,12‐DIMETHYLBENZ(A)ANTHRACENE
K. B. SUKUMARAN, Ronald G. Harvey
Abstract
K. B. SUKUMARAN, Ronald G. Harvey
Abstract
Abstract Das Benzanthracen (I) wird in die isomeren Hydroxyderivate (II) übergeführt, deren Oxidation nach Swern die isomeren Ketone (IIIa) und (IIIb) liefert, die chromatographisch getrennt werden.
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Abstract Das Benzanthracen (I) wird in die isomeren Hydroxyderivate (II) übergeführt, deren Oxidation nach Swern die isomeren Ketone (IIIa) und (IIIb) liefert, die chromatographisch getrennt werden.
Key concepts: 7,12-Dimethylbenz[a]anthracene, Chemistry, Swern oxidation, Anthracene, Metabolite, Carcinogen, Ketone, Medicinal chemistry