2011Journal of the Vacuum Society of JapanOpen access

A Study of Active Oxygen Sterilization System Used an Ultraviolet Irradiation

Kiyoshi Yoshino, Hiroyuki Matsumoto, Tatsuyuki Iwasaki, Shinobu Kinoshita, Kazutoshi Noda, Satoru Iwamori

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Abstract

An advanced sterilization system using exited oxygen species, such as exited singlet oxygen molecules (1O2) and exited singlet atomic oxygen (O(1D)), by ultraviolet irradiations was investigated. Viability of Geobacillus stearothermophilus spore was estimated with a biological indicator (BI) in the active oxygen sterilization (AOS) system. Survival curves of Geobacillus stearothermophilus spore showed exponential reduction. Decimal reduction time (D-value) was found to be 6.8 min., when the active oxygen was irradiated by four or five UV lamps. It was found that Geobacillus stearothermophilus spore was not sterilized by the UV irradiation, but the active oxygen irradiation. We believe that this sterilization system can be applied for medical device sterilization as a new sterilizer.

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An advanced sterilization system using exited oxygen species, such as exited singlet oxygen molecules (1O2) and exited singlet atomic oxygen (O(1D)), by ultraviolet irradiations was investigated. Viability of Geobacillus stearothermophilus spore was estimated with a biological indicator (BI) in the active oxygen sterilization (AOS) system. Survival curves of Geobacillus stearothermophilus spore showed exponential reduction. Decimal reduction time (D-value) was found to be 6.8 min., when the active oxygen was irradiated by four or five UV lamps. It was found that Geobacillus stearothermophilus spore was not sterilized by the UV irradiation, but the active oxygen irradiation. We believe that this sterilization system can be applied for medical device sterilization as a new sterilizer.

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Available abstract

An advanced sterilization system using exited oxygen species, such as exited singlet oxygen molecules (1O2) and exited singlet atomic oxygen (O(1D)), by ultraviolet irradiations was investigated. Viability of Geobacillus stearothermophilus spore was estimated with a biological indicator (BI) in the active oxygen sterilization (AOS) system. Survival curves of Geobacillus stearothermophilus spore showed exponential reduction. Decimal reduction time (D-value) was found to be 6.8 min., when the active oxygen was irradiated by four or five UV lamps. It was found that Geobacillus stearothermophilus spore was not sterilized by the UV irradiation, but the active oxygen irradiation. We believe that this sterilization system can be applied for medical device sterilization as a new sterilizer.

Key concepts: Sterilization (economics), Geobacillus stearothermophilus, D-value, Oxygen, Irradiation, Singlet oxygen, Ultraviolet, Chemistry

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