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Antidiuretic Effect of Posterior-Pituitary Extract in Completely and Partially Hypophysectomized Rats.

Gui-Hai Chen, Eugene M. K. Geiling

Abstract

Water diuresis in rats is greatly decreased both in rate and in quantity by complete hypophysectomy or by removal of the anterior hypophysis. Completely hypophysectomized rats are not suitable for the estimation of the antidiuretic principle of the posterior hypophysis. Rats after removal of the posterior hypophysis respond to the antidiuretic principle of the posterior-pituitary extract similarly as the normal animals.

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Key concepts: Hypophysectomy, Antidiuretic, Posterior pituitary, Diuresis, Internal medicine, Endocrinology, Pituitary gland, Biology