Chiral Recognition of Mandelic Acid by L-MA Derivative-Modified Sensor in Liquid Environment

This study demonstrates a new approach for the highly selective molecular recognition of chiral mandelic acid using an L-mandelic acid derivative with an optically active hydroxyl group as the selector. The proposed method is based on quartz crystal microbalance (QCM) detection combined with functional multilayer film techniques in a liquid environment. The present chiral recognition results suggest that the L-mandelic acid derivative is an excellent resolving agent for detecting chiral mandelic acid.