Mechanisms of Antiulcerogenic Effect of Garlic (Allium sativum) in Albino Rats
Salaudeen Tope
Abstract
Salaudeen Tope
Abstract
Aims: The aim of the present study was to investigate the possible effects of garlic juice, as well as feed supplemented with Allium sativum , on gastric ulceration, antioxidant activity and gastric mucus cell count in wistar rats. Study Design: The albino rats were divided into six groups each group containing eight animals and treated for 30 days. A low dose (250mg/kg body weight) and high dose (500mg/kg) of garlic juice was orally administered to two of the experimental groups, while two other groups were fed with 5% and 10% Allium sativum/ standard feed mix. The control group was fed on the standard rats’ feed and water only, while a positive control group was given Misoprostol (10 �gkg -1
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Aims: The aim of the present study was to investigate the possible effects of garlic juice, as well as feed supplemented with Allium sativum , on gastric ulceration, antioxidant activity and gastric mucus cell count in wistar rats. Study Design: The albino rats were divided into six groups each group containing eight animals and treated for 30 days. A low dose (250mg/kg body weight) and high dose (500mg/kg) of garlic juice was orally administered to two of the experimental groups, while two other groups were fed with 5% and 10% Allium sativum/ standard feed mix. The control group was fed on the standard rats’ feed and water only, while a positive control group was given Misoprostol (10 �gkg -1
Key concepts: Allium sativum, Traditional medicine, Allium, Sativum, Antioxidant, Chemistry, Biology, Food science