1988Japanese Journal of Oral & Maxillofacial SurgeryOpen access

A case of carcinoma in pleomorphic adenoma in the palate.

Kazumasa SUGIHARA, Hiroshi MUKAI, Kiyomi KAWASHIMA, Noriko Yamashita, Tetsuro Ishigami, Sukehide YAMASHITA

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Abstract

Malignant mixed tumors are rare and reported to comprise from 3 to 10% of the total salivary gland neoplasms.This tumor is interpreted as a malignant transformation within an already existing benign pleomorphic adenoma.This report represents a case of carcinoma in pleomorphic adenoma in the palate which developed from benign pleomophic adenoma.Case: A 66-year-old female was referred to our clinic with a slowly enlarging, painless mass in the hard palate.Surgical removal of this tumor was accomplished, and histopathological diagnosis was benign pleomorphic adenoma.Two years later she revisited us complaining of rapidly growing recurrent tumor in the same palate site.Histopathological diagnosis of the surgically removed specimen was carcinoma in pleomorphic adenoma.After radical resection of the tumor the patient had no recurrence for about 9 years.

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Malignant mixed tumors are rare and reported to comprise from 3 to 10% of the total salivary gland neoplasms.This tumor is interpreted as a malignant transformation within an already existing benign pleomorphic adenoma.This report represents a case of carcinoma in pleomorphic adenoma in the palate which developed from benign pleomophic adenoma.Case: A 66-year-old female was referred to our clinic with a slowly enlarging, painless mass in the hard palate.Surgical removal of this tumor was accomplished, and histopathological diagnosis was benign pleomorphic adenoma.Two years later she revisited us complaining of rapidly growing recurrent tumor in the same palate site.Histopathological diagnosis of the surgically removed specimen was carcinoma in pleomorphic adenoma.After radical resection of the tumor the patient had no recurrence for about 9 years.

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Available abstract

Malignant mixed tumors are rare and reported to comprise from 3 to 10% of the total salivary gland neoplasms.This tumor is interpreted as a malignant transformation within an already existing benign pleomorphic adenoma.This report represents a case of carcinoma in pleomorphic adenoma in the palate which developed from benign pleomophic adenoma.Case: A 66-year-old female was referred to our clinic with a slowly enlarging, painless mass in the hard palate.Surgical removal of this tumor was accomplished, and histopathological diagnosis was benign pleomorphic adenoma.Two years later she revisited us complaining of rapidly growing recurrent tumor in the same palate site.Histopathological diagnosis of the surgically removed specimen was carcinoma in pleomorphic adenoma.After radical resection of the tumor the patient had no recurrence for about 9 years.

Key concepts: Pleomorphic adenoma, Medicine, Malignant transformation, Benign tumor, Adenoma, Mixed tumor, Hard palate, Carcinoma ex pleomorphic adenoma

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