Hematology: Fatal Ingestion of a Brodifacoum-Containing Rodenticide
Robin A. Helmuth, Donald W. McCloskey, David J. Doedens, Dean A. Hawley
Abstract
Robin A. Helmuth, Donald W. McCloskey, David J. Doedens, Dean A. Hawley
Abstract
Inhibition of normal clotting is a result of rodenticides being applied to rodents in an effort to exterminate them. However, the rodenticides are also readily available for human consumption. We report a fatal ingestion of brodifacoum, a long-acting warfarin-like anticoagulant found in Havoc rodenticide. To our knowledge, this is the first such fatality reported. This case illustrates the typical clinical presentation, therapeutic alternatives, and responses to vitamin K-antagonizing anticoagulant overdoses.
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Inhibition of normal clotting is a result of rodenticides being applied to rodents in an effort to exterminate them. However, the rodenticides are also readily available for human consumption. We report a fatal ingestion of brodifacoum, a long-acting warfarin-like anticoagulant found in Havoc rodenticide. To our knowledge, this is the first such fatality reported. This case illustrates the typical clinical presentation, therapeutic alternatives, and responses to vitamin K-antagonizing anticoagulant overdoses.
Key concepts: Brodifacoum, Rodenticide, Ingestion, Warfarin, Anticoagulant, Medicine, Toxicology, Intensive care medicine