1989Laboratory MedicineRequires access

Hematology: Fatal Ingestion of a Brodifacoum-Containing Rodenticide

Robin A. Helmuth, Donald W. McCloskey, David J. Doedens, Dean A. Hawley

Open publisher page 22 citations

Abstract

Inhibition of normal clotting is a result of rodenticides being applied to rodents in an effort to exterminate them. However, the rodenticides are also readily available for human consumption. We report a fatal ingestion of brodifacoum, a long-acting warfarin-like anticoagulant found in Havoc rodenticide. To our knowledge, this is the first such fatality reported. This case illustrates the typical clinical presentation, therapeutic alternatives, and responses to vitamin K-antagonizing anticoagulant overdoses.

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What this paper is about

Inhibition of normal clotting is a result of rodenticides being applied to rodents in an effort to exterminate them. However, the rodenticides are also readily available for human consumption. We report a fatal ingestion of brodifacoum, a long-acting warfarin-like anticoagulant found in Havoc rodenticide. To our knowledge, this is the first such fatality reported. This case illustrates the typical clinical presentation, therapeutic alternatives, and responses to vitamin K-antagonizing anticoagulant overdoses.

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OpenAlex reports 22 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Inhibition of normal clotting is a result of rodenticides being applied to rodents in an effort to exterminate them. However, the rodenticides are also readily available for human consumption. We report a fatal ingestion of brodifacoum, a long-acting warfarin-like anticoagulant found in Havoc rodenticide. To our knowledge, this is the first such fatality reported. This case illustrates the typical clinical presentation, therapeutic alternatives, and responses to vitamin K-antagonizing anticoagulant overdoses.

Key concepts: Brodifacoum, Rodenticide, Ingestion, Warfarin, Anticoagulant, Medicine, Toxicology, Intensive care medicine

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