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Fungal Keratitis Caused by Colletotrichum gloeosporioides

Noriaki Yamamoto, Tadahiko Matsumoto, Yasuhisa Ishibashi

Open publisher page 35 citations

Abstract

PURPOSE: To describe a case of fungal keratitis caused by a rare coelomycete pathogen, Colletotrichum gloeosporioides. METHODS: An 82-year-old man with myelodysplastic syndrome developed fungal keratitis 6 months after cataract surgery in the left eye. Because the findings of the anterior chamber deteriorated after the initiation of natamycin, additional treatment with topical and systemic fluconazole was initiated. RESULTS: The isolates of corneal scraping grew C. gloeosporioides. After antifungal treatment of 2 months, the corneal lesion resolved with no recurrence of infection over a 5-year follow-up period. CONCLUSIONS: A combination treatment of natamycin and fluconazole was effective in the treatment of C. gloeosporioides.

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What this paper is about

PURPOSE: To describe a case of fungal keratitis caused by a rare coelomycete pathogen, Colletotrichum gloeosporioides. METHODS: An 82-year-old man with myelodysplastic syndrome developed fungal keratitis 6 months after cataract surgery in the left eye. Because the findings of the anterior chamber deteriorated after the initiation of natamycin, additional treatment with topical and systemic fluconazole was initiated. RESULTS: The isolates of corneal scraping grew C. gloeosporioides. After antifungal treatment of 2 months, the corneal lesion resolved with no recurrence of infection over a 5-year follow-up period. CONCLUSIONS: A combination treatment of natamycin and fluconazole was effective in the treatment of C. gloeosporioides.

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Available abstract

PURPOSE: To describe a case of fungal keratitis caused by a rare coelomycete pathogen, Colletotrichum gloeosporioides. METHODS: An 82-year-old man with myelodysplastic syndrome developed fungal keratitis 6 months after cataract surgery in the left eye. Because the findings of the anterior chamber deteriorated after the initiation of natamycin, additional treatment with topical and systemic fluconazole was initiated. RESULTS: The isolates of corneal scraping grew C. gloeosporioides. After antifungal treatment of 2 months, the corneal lesion resolved with no recurrence of infection over a 5-year follow-up period. CONCLUSIONS: A combination treatment of natamycin and fluconazole was effective in the treatment of C. gloeosporioides.

Key concepts: Natamycin, Fungal keratitis, Colletotrichum gloeosporioides, Fluconazole, Keratitis, Antifungal, Medicine, Dermatology

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